Table 1 In vitro dissolution and disintegration constants (p 0.05)
| Radiopharmaceutical | Dissolution velocity Constant (min-1) (n = 6) | Disintegration velocity Constant (min-1) (n = 6) |
|---|---|---|
| 99mTc-MIBI | (0.05 ± 0.02) all pH range | (0.04 ± 0.01) all pH range |
| 99mTc-ECD | (0.040 ± 0.005) all pH range |
(0.05 ± 0.01) (pH 1) (0.09 ± 0.01) (pH4 and 7) |
| 99mTc-MDP | (0.020 ± 0.005) all pH range |
(0.20 ± 0.04) (pH 1 and 7) (0.040 ± 0.005) (pH 4) |
| 99mTc-DTPA |
(0.06 ± 0.01) (pH1and 7) (0.11 ± 0.02) (pH 4) |
0.011 ± 0.002 (pH1and 7) 0.080 ± 0.006 (pH 4) |